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p87 and p101 Subunits Are Distinct Regulators Determining Class I(B) Phosphoinositide 3-Kinase (PI3K) Specificity
Class I(B) phosphoinositide 3-kinase γ (PI3Kγ) comprises a single catalytic p110γ subunit, which binds to two non-catalytic subunits, p87 or p101, and controls a plethora of fundamental cellular responses. The non-catalytic subunits are assumed to be redundant adaptors for Gβγ enabling G-protein-cou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829419/ https://ncbi.nlm.nih.gov/pubmed/24014027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508234 |
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