p87 and p101 Subunits Are Distinct Regulators Determining Class I(B) Phosphoinositide 3-Kinase (PI3K) Specificity

Class I(B) phosphoinositide 3-kinase γ (PI3Kγ) comprises a single catalytic p110γ subunit, which binds to two non-catalytic subunits, p87 or p101, and controls a plethora of fundamental cellular responses. The non-catalytic subunits are assumed to be redundant adaptors for Gβγ enabling G-protein-cou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shymanets, Aliaksei, Prajwal, Bucher, Kirsten, Beer-Hammer, Sandra, Harteneck, Christian, Nürnberg, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829419/
https://ncbi.nlm.nih.gov/pubmed/24014027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508234
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