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Small, mobile FcεRI aggregates are signaling competent
Crosslinking of IgE-bound FcεRI triggers mast cell degranulation. Previous FRAP and phosphorescent anisotropy studies suggested that FcεRI must immobilize to signal. Here, single quantum dot (QD) tracking and hyperspectral microscopy methods are used to redefine relationships between receptor mobili...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828771/ https://ncbi.nlm.nih.gov/pubmed/19747859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.026 |
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