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Small, mobile FcεRI aggregates are signaling competent

Crosslinking of IgE-bound FcεRI triggers mast cell degranulation. Previous FRAP and phosphorescent anisotropy studies suggested that FcεRI must immobilize to signal. Here, single quantum dot (QD) tracking and hyperspectral microscopy methods are used to redefine relationships between receptor mobili...

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書誌詳細
主要な著者: Andrews, Nicholas L., Pfeiffer, Janet R., Martinez, A. Marina, Haaland, David M., Davis, Ryan W., Kawakami, Toshiaki, Oliver, Janet M., Wilson, Bridget S., Lidke, Diane S.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828771/
https://ncbi.nlm.nih.gov/pubmed/19747859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.026
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