Small, mobile FcεRI aggregates are signaling competent

Crosslinking of IgE-bound FcεRI triggers mast cell degranulation. Previous FRAP and phosphorescent anisotropy studies suggested that FcεRI must immobilize to signal. Here, single quantum dot (QD) tracking and hyperspectral microscopy methods are used to redefine relationships between receptor mobili...

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Main Authors: Andrews, Nicholas L., Pfeiffer, Janet R., Martinez, A. Marina, Haaland, David M., Davis, Ryan W., Kawakami, Toshiaki, Oliver, Janet M., Wilson, Bridget S., Lidke, Diane S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828771/
https://ncbi.nlm.nih.gov/pubmed/19747859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.026
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