Formation of a Mast Cell Synapse: FcεRI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on Surfaces

High affinity IgE receptors (FcεRI) on mast cells form a “synapse” when presented with mobile, bilayer incorporated antigen. Here, we show that receptor reorganization within the contacting mast cell membrane is markedly different upon binding of mobile and immobilized ligands. Rat basophilic leukem...

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Hauptverfasser: Carroll-Portillo, Amanda, Spendier, Kathrin, Pfeiffer, Janet, Griffiths, Gary, Li, Haitao, Lidke, Keith A., Oliver, Janet M., Lidke, Diane S., Thomas, James L., Wilson, Bridget S., Timlin, Jerilyn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087819/
https://ncbi.nlm.nih.gov/pubmed/20042583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903071
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