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The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia

BACKGROUND AND PURPOSE: Sphingosine-1-phosphate and its receptors may be involved in vascular smooth muscle cell (VSMC) proliferation following vascular injury. Here, we evaluate the effect of d-erythro-N,N-dimethylsphingosine (DMS), a sphingosine kinase (SK) inhibitor, on VSMC proliferation, apopto...

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Detalhes bibliográficos
Main Authors: McDonald, Robert A, Pyne, Susan, Pyne, Nigel J, Grant, Anne, Wainwright, Cherry L, Wadsworth, Roger M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828019/
https://ncbi.nlm.nih.gov/pubmed/20015089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00533.x
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