Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome

The glomerular basement membrane (GBM) is a key component of the filtering unit in the kidney. Mutations involving any of the collagen IV genes (COL4A3, COL4A4, and COL4A5) affect GBM assembly and cause Alport syndrome, a progressive hereditary kidney disease with no definitive therapy. Previously,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Mari, Asada, Misako, Higashi, Atsuko Y., Nakamura, Jin, Oguchi, Akiko, Tomita, Mayumi, Yamada, Sachiko, Asada, Nariaki, Takase, Masayuki, Okuda, Tomohiko, Kawachi, Hiroshi, Economides, Aris N., Robertson, Elizabeth, Takahashi, Satoru, Sakurai, Takeshi, Goldschmeding, Roel, Muso, Eri, Fukatsu, Atsushi, Kita, Toru, Yanagita, Motoko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827946/
https://ncbi.nlm.nih.gov/pubmed/20197625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39569
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak