Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

In chronic kidney disease, fibroblast dysfunction causes renal fibrosis and renal anemia. Renal fibrosis is mediated by the accumulation of myofibroblasts, whereas renal anemia is mediated by the reduced production of fibroblast-derived erythropoietin, a hormone that stimulates erythropoiesis. Despi...

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Detalhes bibliográficos
Main Authors: Asada, Nariaki, Takase, Masayuki, Nakamura, Jin, Oguchi, Akiko, Asada, Misako, Suzuki, Norio, Yamamura, Ken-ichi, Nagoshi, Narihito, Shibata, Shinsuke, Rao, Tata Nageswara, Fehling, Hans Joerg, Fukatsu, Atsushi, Minegishi, Naoko, Kita, Toru, Kimura, Takeshi, Okano, Hideyuki, Yamamoto, Masayuki, Yanagita, Motoko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195468/
https://ncbi.nlm.nih.gov/pubmed/21911936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57301
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