Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase

Mycobacterium tuberculosis (Mtb) remains the leading single cause of death from bacterial infection. Here we explored the possibility of species-selective inhibition of lipoamide dehydrogenase (Lpd), an enzyme central to Mtb’s intermediary metabolism and antioxidant defense. High-throughput screenin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bryk, Ruslana, Arango, Nancy, Venugopal, Aditya, Warren, J. David, Park, Yun-Hee, Patel, Mulchand S., Lima, Christopher D., Nathan, Carl
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827632/
https://ncbi.nlm.nih.gov/pubmed/20078138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9016186
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker