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Inhibitors Selective for Mycobacterial versus Human Proteasomes
Many anti-infectives inhibit the synthesis of bacterial proteins, but none selectively inhibits their degradation. Most anti-infectives kill replicating pathogens, but few preferentially kill pathogens that have been forced into a non-replicating state by conditions in the host. To explore these alt...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172082/ https://ncbi.nlm.nih.gov/pubmed/19759536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08357 |
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