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Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome
Mycobacterium tuberculosis (Mtb) possesses a proteasome system analogous to the eukaryotic ubiquitin-proteasome pathway. Mtb requires the proteasome to resist killing by the host immune system. The detailed assembly process and the gating mechanism of Mtb proteasome have remained unknown. Using cryo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892373/ https://ncbi.nlm.nih.gov/pubmed/20461058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.95 |
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