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Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome

Mycobacterium tuberculosis (Mtb) possesses a proteasome system analogous to the eukaryotic ubiquitin-proteasome pathway. Mtb requires the proteasome to resist killing by the host immune system. The detailed assembly process and the gating mechanism of Mtb proteasome have remained unknown. Using cryo...

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Autors principals: Li, Dongyang, Li, Hua, Wang, Tao, Pan, Hong, Lin, Gang, Li, Huilin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892373/
https://ncbi.nlm.nih.gov/pubmed/20461058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.95
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