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Mechanism of potassium channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore

Potassium channels allow K(+) ions to easily diffuse through their pores while effectively preventing smaller Na(+) ions from permeation. The ability to discriminate between these two similar and abundant ions is vital for these proteins to control electrical and chemical activity in all organisms....

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Hlavní autoři: Thompson, Ameer N., Kim, Ilsoo, Panosian, Timothy D., Iverson, Tina M., Allen, Toby W., Nimigean, Crina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825899/
https://ncbi.nlm.nih.gov/pubmed/19946269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1703
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