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Pore Hydration States of KcsA Potassium Channels in Membranes

Water-filled hydrophobic cavities in channel proteins serve as gateways for transfer of ions across membranes, but their properties are largely unknown. We determined water distributions along the conduction pores in two tetrameric channels embedded in lipid bilayers using neutron diffraction: potas...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Blasic, Joseph R., Worcester, David L., Gawrisch, Klaus, Gurnev, Philip, Mihailescu, Mihaela
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646329/
https://ncbi.nlm.nih.gov/pubmed/26370089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661819
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