Pore Hydration States of KcsA Potassium Channels in Membranes

Water-filled hydrophobic cavities in channel proteins serve as gateways for transfer of ions across membranes, but their properties are largely unknown. We determined water distributions along the conduction pores in two tetrameric channels embedded in lipid bilayers using neutron diffraction: potas...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Blasic, Joseph R., Worcester, David L., Gawrisch, Klaus, Gurnev, Philip, Mihailescu, Mihaela
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646329/
https://ncbi.nlm.nih.gov/pubmed/26370089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661819
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