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Modeling Permeation Energetics in the KcsA Potassium Channel

The thermodynamics of cation permeation through the KcsA K(+) channel selectivity filter is studied from the perspective of a physically transparent semimicroscopic model using Monte Carlo free energy integration. The computational approach chosen permits dissection of the separate contributions to...

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Bibliografiske detaljer
Main Authors: Garofoli, S., Jordan, P. C.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302847/
https://ncbi.nlm.nih.gov/pubmed/12719216
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