Mechanism of potassium channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore

Potassium channels allow K(+) ions to easily diffuse through their pores while effectively preventing smaller Na(+) ions from permeation. The ability to discriminate between these two similar and abundant ions is vital for these proteins to control electrical and chemical activity in all organisms....

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Bibliographic Details
Main Authors:	Thompson, Ameer N., Kim, Ilsoo, Panosian, Timothy D., Iverson, Tina M., Allen, Toby W., Nimigean, Crina M.
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2825899/ https://ncbi.nlm.nih.gov/pubmed/19946269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1703
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Mechanism of potassium channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore

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