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Chelator Fragment Libraries for Targeting Metalloproteinases
[Image: see text] A chelator fragment library based on a variety of metal binding groups was screened against a metalloproteinase. Lead hits were identified and an expanded library of select compounds was synthesized, resulting in numerous high-affinity hits against several metalloprotein targets. T...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825879/ https://ncbi.nlm.nih.gov/pubmed/20058293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900516 |
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