Chelator Fragment Libraries for Targeting Metalloproteinases

[Image: see text] A chelator fragment library based on a variety of metal binding groups was screened against a metalloproteinase. Lead hits were identified and an expanded library of select compounds was synthesized, resulting in numerous high-affinity hits against several metalloprotein targets. T...

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Detaylı Bibliyografya
Asıl Yazarlar: Agrawal, Arpita, Johnson, Sherida L., Jacobsen, Jennifer A., Miller, Melissa T., Chen, Li-Hsing, Pellecchia, Maurizio, Cohen, Seth M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825879/
https://ncbi.nlm.nih.gov/pubmed/20058293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900516
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