Targeting Metallo-proteins by Fragment-Based Lead Discovery

It has been estimated that nearly one third of functional proteins contain a metal ion. These constitute a wide variety of possible drug targets including metalloproteinases, dehydrogenases, oxidoreductases, hydrolases, deacetylases or many others in which the metal ion is either of catalytic or str...

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Detalhes bibliográficos
Main Authors: Johnson, Sherida, Barile, Elisa, Farina, Biancamaria, Purves, Angela, Wei, Jun, Chen, Li-Hsing, Shiryaev, Sergey, Zhang, Ziming, Rodionova, Irina, Agrawal, Arpita, Cohen, Seth M., Osterman, Andrei, Strongin, Alex, Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135788/
https://ncbi.nlm.nih.gov/pubmed/21564556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2011.01136.x
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