Biochemical Characterization of the Cellular Glycosylphosphatidylinositol-linked Membrane Type-6 Matrix Metalloproteinase

Ubiquitously expressed membrane type-1 matrix metalloproteinase (MT1-MMP), an archetype member of the MMP family, binds tissue inhibitor of metalloproteinases-2 (TIMP-2), activates matrix metalloproteinase-2 (MMP-2), and stimulates cell migration in various cell types. In contrast with MT1-MMP, the...

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Bibliographische Detailangaben
Hauptverfasser: Radichev, Ilian A., Remacle, Albert G., Shiryaev, Sergey A., Purves, Angela N., Johnson, Sherida L., Pellecchia, Maurizio, Strongin, Alex Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871476/
https://ncbi.nlm.nih.gov/pubmed/20308072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107094
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