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Adaptive dose finding based on t-statistic for dose–response trials
The goals of phase II dose–response studies are to prove that the treatment is effective and to choose the dose for further development. Randomized designs with equal allocation to either a high dose and placebo or to each of several doses and placebo are typically used. However, in trials where res...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825484/ https://ncbi.nlm.nih.gov/pubmed/18241082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3209 |
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