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Adaptive dose finding based on t-statistic for dose–response trials

The goals of phase II dose–response studies are to prove that the treatment is effective and to choose the dose for further development. Randomized designs with equal allocation to either a high dose and placebo or to each of several doses and placebo are typically used. However, in trials where res...

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Bibliografski detalji
Glavni autori: Ivanova, Anastasia, Bolognese, James A., Perevozskaya, Inna
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825484/
https://ncbi.nlm.nih.gov/pubmed/18241082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3209
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