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Thermodynamic Analysis of the CSL·Notch Interaction: DISTRIBUTION OF BINDING ENERGY OF THE NOTCH RAM REGION TO THE CSL β-TREFOIL DOMAIN AND THE MODE OF COMPETITION WITH THE VIRAL TRANSACTIVATOR EBNA2

The Notch signaling pathway is a cell-cell communication network giving rise to cell differentiation during metazoan development. Activation of the pathway releases the intracellular portion of the Notch receptor to translocate to the nucleus, where it is able to interact with the effector transcrip...

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Détails bibliographiques
Auteurs principaux: Johnson, Scott E., Ilagan, M. Xenia G., Kopan, Raphael, Barrick, Doug
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825463/
https://ncbi.nlm.nih.gov/pubmed/20028974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019968
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