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Thermodynamic Analysis of the CSL·Notch Interaction: DISTRIBUTION OF BINDING ENERGY OF THE NOTCH RAM REGION TO THE CSL β-TREFOIL DOMAIN AND THE MODE OF COMPETITION WITH THE VIRAL TRANSACTIVATOR EBNA2
The Notch signaling pathway is a cell-cell communication network giving rise to cell differentiation during metazoan development. Activation of the pathway releases the intracellular portion of the Notch receptor to translocate to the nucleus, where it is able to interact with the effector transcrip...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825463/ https://ncbi.nlm.nih.gov/pubmed/20028974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019968 |
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