טוען...
Activation and Inhibition of Histone Deacetylase 8 by Monovalent Cations
The metal-dependent histone deacetylases (HDACs) catalyze hydrolysis of acetyl groups from acetyllysine side chains and are targets of cancer therapeutics. Two bound monovalent cations (MVCs) of unknown function have been previously observed in crystal structures of HDAC8; site 1 is near the active...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825397/ https://ncbi.nlm.nih.gov/pubmed/20029090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033399 |
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