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Oncolysis by an HSV-1 engineered to express cytosine deaminase and a fusogenic glycoprotein for head and neck squamous cell carcinoma
BACKGROUND: A replication-competent, attenuated, oncolytic herpes simplex virus-1, OncoVEX(GALV/CD), has previously been engineered to express a fusogenic protein from the gibbon ape leukemia virus and cytosine deaminase/uracil phosphoribosyltransferase (CD/UPRT) which converts fluorocytosine (5-FC)...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824889/ https://ncbi.nlm.nih.gov/pubmed/20157061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archoto.2009.214 |
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