Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer

BACKGROUND: There are still no effective treatments for superficial bladder cancer (SBC)/non-muscle invasive bladder cancer. Following treatment, 20% of patients still develop metastatic disease. Superficial bladder cancer is often multifocal, has high recurrences after surgical resection and recurs...

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Detalhes bibliográficos
Main Authors: Simpson, G R, Horvath, A, Annels, N E, Pencavel, T, Metcalf, S, Seth, R, Peschard, P, Price, T, Coffin, R S, Mostafid, H, Melcher, A A, Harrington, K J, Pandha, H S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273343/
https://ncbi.nlm.nih.gov/pubmed/22240799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.577
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