Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations

Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages...

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Autors principals: Tuch, Brian B., Laborde, Rebecca R., Xu, Xing, Gu, Jian, Chung, Christina B., Monighetti, Cinna K., Stanley, Sarah J., Olsen, Kerry D., Kasperbauer, Jan L., Moore, Eric J., Broomer, Adam J., Tan, Ruoying, Brzoska, Pius M., Muller, Matthew W., Siddiqui, Asim S., Asmann, Yan W., Sun, Yongming, Kuersten, Scott, Barker, Melissa A., De La Vega, Francisco M., Smith, David I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824832/
https://ncbi.nlm.nih.gov/pubmed/20174472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009317
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