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Mutant Allele Specific Imbalance in Oncogenes with Copy Number Alterations: Occurrence, Mechanisms, and Potential Clinical Implications

Mutant allele specific imbalance (MASI) was initially coined to describe copy number alterations associated with the mutant allele of an oncogene. The copy number gain (CNG) specific to the mutant allele can be readily observed in electropherograms. With the development of genome-wide analyses at ba...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Yu, Chih-Chieh, Qiu, Wanglong, Juang, Caroline S., Mansukhani, Mahesh M., Halmos, Balazs, Su, Gloria H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507770/
https://ncbi.nlm.nih.gov/pubmed/27725226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.10.013
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