טוען...

Oncogene Mutations, Copy Number Gains and Mutant Allele Specific Imbalance (MASI) Frequently Occur Together in Tumor Cells

BACKGROUND: Activating mutations in one allele of an oncogene (heterozygous mutations) are widely believed to be sufficient for tumorigenesis. However, mutant allele specific imbalance (MASI) has been observed in tumors and cell lines harboring mutations of oncogenes. METHODOLOGY/PRINCIPAL FINDINGS:...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Soh, Junichi, Okumura, Naoki, Lockwood, William W., Yamamoto, Hiromasa, Shigematsu, Hisayuki, Zhang, Wei, Chari, Raj, Shames, David S., Tang, Ximing, MacAulay, Calum, Varella-Garcia, Marileila, Vooder, Tõnu, Wistuba, Ignacio I., Lam, Stephen, Brekken, Rolf, Toyooka, Shinichi, Minna, John D., Lam, Wan L., Gazdar, Adi F.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757721/
https://ncbi.nlm.nih.gov/pubmed/19826477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007464
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!