PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

We investigated the frequency and function of mutations and increased copy number of the PIK3CA gene in lung cancers. PIK3CA mutations are one of the most common gene changes present in human cancers. We analyzed the mutational status of exons 9 and 20 and gene copy number of PIK3CA using 86 non–sma...

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Bibliografiske detaljer
Main Authors: Yamamoto, Hiromasa, Shigematsu, Hisayuki, Nomura, Masaharu, Lockwood, William W., Sato, Mitsuo, Okumura, Naoki, Soh, Junichi, Suzuki, Makoto, Wistuba, Ignacio I., Fong, Kwun M., Lee, Huei, Toyooka, Shinichi, Date, Hiroshi, Lam, Wan L., Minna, John D., Gazdar, Adi F.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874836/
https://ncbi.nlm.nih.gov/pubmed/18757405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5084
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