Preferential 8q24 Allelic Imbalance and MYC gene Copy Number in Primary Prostate Cancer

Four independent regions within 8q24 near the MYC gene are associated with risk for prostate cancer. Here we investigated allelic imbalance at 8q24 risk variants and MYC gene DNA copy number (CN) in 27 primary prostate cancers. Heterozygotes were observed in 24 of 27 patients at one or more 8q24 mar...

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Detalhes bibliográficos
Main Authors: Chen, Hankui, Liu, Wanqing, Roberts, Wilmer, Hooker, Stanley, Fedor, Helen, DeMarzo, Angelo, Isaacs, William, Kittles, Rick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963483/
https://ncbi.nlm.nih.gov/pubmed/20634801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pcan.2010.20
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