Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations

Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages...

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Hlavní autoři: Tuch, Brian B., Laborde, Rebecca R., Xu, Xing, Gu, Jian, Chung, Christina B., Monighetti, Cinna K., Stanley, Sarah J., Olsen, Kerry D., Kasperbauer, Jan L., Moore, Eric J., Broomer, Adam J., Tan, Ruoying, Brzoska, Pius M., Muller, Matthew W., Siddiqui, Asim S., Asmann, Yan W., Sun, Yongming, Kuersten, Scott, Barker, Melissa A., De La Vega, Francisco M., Smith, David I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824832/
https://ncbi.nlm.nih.gov/pubmed/20174472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009317
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