CD72 negatively regulates KIT-mediated responses in human mast cells

KIT activation, through binding of its ligand, stem cell factor (SCF), is crucial for normal mast cell growth, differentiation, and survival. Furthermore, KIT may also contribute to mast cell homing and cytokine generation. Activating mutations in KIT lead to the dysregulated mast cell growth associ...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kataoka, Tatsuki R., Kumanogoh, Atsushi, Bandara, Geethani, Metcalfe, Dean D., Gilfillan, Alasdair M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824776/
https://ncbi.nlm.nih.gov/pubmed/20100931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902450
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi