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CD72 negatively regulates KIT-mediated responses in human mast cells
KIT activation, through binding of its ligand, stem cell factor (SCF), is crucial for normal mast cell growth, differentiation, and survival. Furthermore, KIT may also contribute to mast cell homing and cytokine generation. Activating mutations in KIT lead to the dysregulated mast cell growth associ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824776/ https://ncbi.nlm.nih.gov/pubmed/20100931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902450 |
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