PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

The mobilization of metabolic energy from adipocytes depends on a tightly regulated balance between hydrolysis and resynthesis of triacylglycerides (TAGs). Hydrolysis is stimulated by β-adrenergic signalling to PKA that mediates phosphorylation of lipolytic enzymes, including hormone-sensitive lipas...

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Detalhes bibliográficos
Main Authors: Djouder, Nabil, Tuerk, Roland D, Suter, Marianne, Salvioni, Paolo, Thali, Ramon F, Scholz, Roland, Vaahtomeri, Kari, Auchli, Yolanda, Rechsteiner, Helene, Brunisholz, René A, Viollet, Benoit, Mäkelä, Tomi P, Wallimann, Theo, Neumann, Dietbert, Krek, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824464/
https://ncbi.nlm.nih.gov/pubmed/19942859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.339
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