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SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling

AMP-activated protein kinase (AMPK) inhibits several anabolic pathways such as fatty acid and protein synthesis, and identification of AMPK substrate specificity would be useful to understand its role in particular cellular processes and develop strategies to modulate AMPK activity in a substrate-sp...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yan, Yan, Ollila, Saara, Wong, Iris P. L., Vallenius, Tea, Palvimo, Jorma J., Vaahtomeri, Kari, Mäkelä, Tomi P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674823/
https://ncbi.nlm.nih.gov/pubmed/26616021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9979
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