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Ciclopirox Olamine inhibits mTORC1 signaling by activation of AMPK
Ciclopirox olamine (CPX), an off-patent antifungal agent, has recently been identified as a potential anticancer agent. The mammalian target of rapamycin (mTOR) is a central controller of cell growth, proliferation and survival. Little is known about whether and how CPX executes its anticancer actio...
Shranjeno v:
| izdano v: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003681/ https://ncbi.nlm.nih.gov/pubmed/27396756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.07.005 |
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