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Increased α-actinin-1 destabilizes E-cadherin-based adhesions and associates with poor prognosis in basal-like breast cancer

The controlled formation and stabilization of E-cadherin-based adhesions is vital for epithelial integrity. This requires co-operation between the E-cadherin-based adhesions and the associated actin cytoskeleton. In cancer, this co-operation often fails, predisposing cells to migration through molec...

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書目詳細資料
發表在:PLoS One
Main Authors: Kovac, Bianca, Mäkelä, Tomi P., Vallenius, Tea
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942811/
https://ncbi.nlm.nih.gov/pubmed/29742177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196986
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