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ME1 promotes basal-like breast cancer progression and associates with poor prognosis

Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose upt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Liao, Ruocen, Ren, Guoping, Liu, Huixin, Chen, Xingyu, Cao, Qianhua, Wu, Xuebiao, Li, Jun, Dong, Chenfang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233160/
https://ncbi.nlm.nih.gov/pubmed/30425310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35106-y
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