ME1 promotes basal-like breast cancer progression and associates with poor prognosis

Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose upt...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Liao, Ruocen, Ren, Guoping, Liu, Huixin, Chen, Xingyu, Cao, Qianhua, Wu, Xuebiao, Li, Jun, Dong, Chenfang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233160/
https://ncbi.nlm.nih.gov/pubmed/30425310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35106-y
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