Inhibition of UGT8 suppresses basal-like breast cancer progression by attenuating sulfatide–αVβ5 axis

Basal-like breast cancer (BLBC) is associated with a poor clinical outcome as a result of the few treatment options and poor therapeutic response. Here, we report that elevated expression of urine diphosphate–galactose ceramide galactosyltransferase (UGT8) specifically occurs in BLBC and predicts po...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Cao, Qianhua, Chen, Xingyu, Wu, Xuebiao, Liao, Ruocen, Huang, Panpan, Tan, Yanjia, Wang, Li, Ren, Guoping, Huang, Jian, Dong, Chenfang
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987921/
https://ncbi.nlm.nih.gov/pubmed/29728441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172048
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