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Effect of Dioxygen on Copper(II) Binding to α-Synuclein

Using the fluorescent amino acid tryptophan (Trp), we have characterized the copper(II) binding of F4W α-synuclein in the presence and absence of dioxygen at neutral pH. Variations in Trp fluorescence indicate that copper(II) binding is enhanced by the presence of dioxygen, with the apparent dissoci...

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Autors principals: Lucas, Heather R., Lee, Jennifer C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824066/
https://ncbi.nlm.nih.gov/pubmed/20064662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2009.12.010
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