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Identification of the Minimal Copper(II)-binding α-Synuclein Sequence

Parkinson’s disease has been long linked to environmental factors, such as transition metals and recently to α-synuclein, a presynaptic protein. Using tryptophan-containing peptides, we identified the minimal Cu(II)-binding sequence to be within the first four residues, MDV(F/W), anchored by the α-a...

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Detalhes bibliográficos
Main Authors: Jackson, Mark S., Lee, Jennifer C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768475/
https://ncbi.nlm.nih.gov/pubmed/19780617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic901157w
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