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Effect of Dioxygen on Copper(II) Binding to α-Synuclein

Using the fluorescent amino acid tryptophan (Trp), we have characterized the copper(II) binding of F4W α-synuclein in the presence and absence of dioxygen at neutral pH. Variations in Trp fluorescence indicate that copper(II) binding is enhanced by the presence of dioxygen, with the apparent dissoci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lucas, Heather R., Lee, Jennifer C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824066/
https://ncbi.nlm.nih.gov/pubmed/20064662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2009.12.010
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