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Modulation of Astrocyte Glutamate Transporters Decreases Seizures in a Mouse Model of Tuberous Sclerosis Complex

Astrocyte dysfunction may contribute to epileptogenesis and other neurological deficits in Tuberous Sclerosis Complex (TSC). In particular, decreased expression and function of astrocyte glutamate transporters have been implicated in causing elevated extracellular glutamate levels, neuronal death, a...

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Detalles Bibliográficos
Autores principales: Zeng, Ling-Hui, Bero, Adam W., Zhang, Bo, Holtzman, David M., Wong, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823985/
https://ncbi.nlm.nih.gov/pubmed/20045054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.12.020
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