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Postnatal Reduction of Tuberous Sclerosis Complex-1 Expression in Astrocytes and Neurons Causes Seizures in an Age-Dependent Manner

OBJECTIVE: Epilepsy is one of the most prominent symptoms of the genetic disorder, tuberous sclerosis complex (TSC), and may be related to developmental defects resulting from impaired TSC1 or TSC2 gene function in astrocytes and neurons. Inactivation of the Tsc1 gene driven by a glial-fibrillary ac...

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Bibliografski detalji
Izdano u:Epilepsia
Glavni autori: Zou, Jia, Zhang, Bo, Gutmann, David H, Wong, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716871/
https://ncbi.nlm.nih.gov/pubmed/29023667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13923
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