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Postnatal Reduction of Tuberous Sclerosis Complex-1 Expression in Astrocytes and Neurons Causes Seizures in an Age-Dependent Manner

OBJECTIVE: Epilepsy is one of the most prominent symptoms of the genetic disorder, tuberous sclerosis complex (TSC), and may be related to developmental defects resulting from impaired TSC1 or TSC2 gene function in astrocytes and neurons. Inactivation of the Tsc1 gene driven by a glial-fibrillary ac...

詳細記述

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書誌詳細
出版年:Epilepsia
主要な著者: Zou, Jia, Zhang, Bo, Gutmann, David H, Wong, Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716871/
https://ncbi.nlm.nih.gov/pubmed/29023667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13923
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