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Postnatal Reduction of Tuberous Sclerosis Complex-1 Expression in Astrocytes and Neurons Causes Seizures in an Age-Dependent Manner
OBJECTIVE: Epilepsy is one of the most prominent symptoms of the genetic disorder, tuberous sclerosis complex (TSC), and may be related to developmental defects resulting from impaired TSC1 or TSC2 gene function in astrocytes and neurons. Inactivation of the Tsc1 gene driven by a glial-fibrillary ac...
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| 出版年: | Epilepsia |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716871/ https://ncbi.nlm.nih.gov/pubmed/29023667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13923 |
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