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Postnatal Reduction of Tuberous Sclerosis Complex-1 Expression in Astrocytes and Neurons Causes Seizures in an Age-Dependent Manner
OBJECTIVE: Epilepsy is one of the most prominent symptoms of the genetic disorder, tuberous sclerosis complex (TSC), and may be related to developmental defects resulting from impaired TSC1 or TSC2 gene function in astrocytes and neurons. Inactivation of the Tsc1 gene driven by a glial-fibrillary ac...
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| Udgivet i: | Epilepsia |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716871/ https://ncbi.nlm.nih.gov/pubmed/29023667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13923 |
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