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Modulation of Astrocyte Glutamate Transporters Decreases Seizures in a Mouse Model of Tuberous Sclerosis Complex

Astrocyte dysfunction may contribute to epileptogenesis and other neurological deficits in Tuberous Sclerosis Complex (TSC). In particular, decreased expression and function of astrocyte glutamate transporters have been implicated in causing elevated extracellular glutamate levels, neuronal death, a...

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Detalhes bibliográficos
Main Authors: Zeng, Ling-Hui, Bero, Adam W., Zhang, Bo, Holtzman, David M., Wong, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823985/
https://ncbi.nlm.nih.gov/pubmed/20045054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.12.020
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