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Impaired Astrocytic Gap Junction Coupling and Potassium Buffering in a Mouse Model of Tuberous Sclerosis Complex

Abnormalities in astrocytes occur in the brains of patients with Tuberous Sclerosis Complex (TSC) and may contribute to the pathogenesis of neurological dysfunction in this disease. Here, we report that knock-out mice with Tsc1 gene inactivation in glia (Tsc1(GFAP)CKO mice) exhibit decreased express...

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Detalhes bibliográficos
Main Authors: Xu, Lin, Zeng, Ling-Hui, Wong, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764295/
https://ncbi.nlm.nih.gov/pubmed/19385061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.01.010
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