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Impaired Astrocytic Gap Junction Coupling and Potassium Buffering in a Mouse Model of Tuberous Sclerosis Complex
Abnormalities in astrocytes occur in the brains of patients with Tuberous Sclerosis Complex (TSC) and may contribute to the pathogenesis of neurological dysfunction in this disease. Here, we report that knock-out mice with Tsc1 gene inactivation in glia (Tsc1(GFAP)CKO mice) exhibit decreased express...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764295/ https://ncbi.nlm.nih.gov/pubmed/19385061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.01.010 |
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