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Impaired Astrocytic Gap Junction Coupling and Potassium Buffering in a Mouse Model of Tuberous Sclerosis Complex

Abnormalities in astrocytes occur in the brains of patients with Tuberous Sclerosis Complex (TSC) and may contribute to the pathogenesis of neurological dysfunction in this disease. Here, we report that knock-out mice with Tsc1 gene inactivation in glia (Tsc1(GFAP)CKO mice) exhibit decreased express...

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Bibliografiska uppgifter
Huvudupphovsmän: Xu, Lin, Zeng, Ling-Hui, Wong, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764295/
https://ncbi.nlm.nih.gov/pubmed/19385061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.01.010
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