Glutamate Transport Decreases Mitochondrial pH and Modulates Oxidative Metabolism in Astrocytes

During synaptic activity, the clearance of neuronally released glutamate leads to an intracellular sodium concentration increase in astrocytes that is associated with significant metabolic cost. The proximity of mitochondria at glutamate uptake sites in astrocytes raises the question of the ability...

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Publicat a:J Neurosci
Autors principals: Azarias, Guillaume, Perreten, Hélène, Lengacher, Sylvain, Poburko, Damon, Demaurex, Nicolas, Magistretti, Pierre J., Chatton, Jean-Yves
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622778/
https://ncbi.nlm.nih.gov/pubmed/21389211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4378-10.2011
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